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The exosome and heterochromatin: multilevel regulation of gene silencing.

Abstract:

Heterochromatic silencing is important for repressing gene expression, protecting cells against viral invasion, maintaining DNA integrity and for proper chromosome segregation. Recently, it has become apparent that expression of eukaryotic genomes is far more complex than had previously been anticipated. Strikingly, it has emerged that most of the genome is transcribed including intergenic regions and heterochromatin, calling for us to re-address the question of how gene silencing is regulate...

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Publication status:
Published

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Publisher copy:
10.1007/978-1-4419-7841-7_9

Authors


Vasiljeva, L More by this author
Journal:
Advances in experimental medicine and biology
Volume:
702
Pages:
105-121
Publication date:
2010
DOI:
ISSN:
0065-2598
URN:
uuid:608d810b-3487-45b5-8afa-e1d799903cb6
Source identifiers:
311056
Local pid:
pubs:311056

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