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TNF alpha is an effective therapeutic target for rheumatoid arthritis.

Abstract:

Rheumatoid arthritis is the most common of a number of diseases in which inflammation and tissue destruction is driven by an autoimmune process. Current therapy is inadequate, and this has prompted major research efforts, both in academia and industry, to understand more about the pathogenesis, and hence provide the rationale for new therapeutic strategies. Here we review our studies of cytokine expression and regulation in rheumatoid joints, which has culminated in demonstrating that TNF alp...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Annals of the New York Academy of Sciences
Volume:
766
Issue:
1 Receptor Acti
Pages:
272-278
Publication date:
1995-09-05
DOI:
EISSN:
1749-6632
ISSN:
0077-8923
URN:
uuid:6052cea5-77a4-4efe-bae0-e391a1c531ba
Source identifiers:
481634
Local pid:
pubs:481634

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