Journal article
Genomewide meta‐analysis identifies loci associated with IGF‐I and IGFBP‐3 levels with impact on age‐related traits
- Abstract:
-
The growth hormone/insulin‐like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF‐related proteins including IGF‐I and IGF‐binding protein‐3 (IGFBP‐3) have also been implicated in risk of human diseases including cardiovascular diseases, diabetes, and cancer. Through genomewide association study of up to 30 884 adults of European ancestry from 21 studies, we confirmed and extended the list of previously identified loci associated with circulating IGF‐I...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 822.5KB, Terms of use)
-
- Publisher copy:
- 10.1111/acel.12490
Authors
Bibliographic Details
- Publisher:
- Wiley
- Journal:
- Aging cell More from this journal
- Volume:
- 15
- Issue:
- 5
- Pages:
- 811-824
- Publication date:
- 2016-10-01
- Acceptance date:
- 2016-04-01
- DOI:
- EISSN:
-
1474-9726
- ISSN:
-
1474-9718
- Pmid:
-
27329260
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:630019
- UUID:
-
uuid:603b2ab3-90c8-445d-829e-fc70d763c300
- Local pid:
-
pubs:630019
- Source identifiers:
-
630019
- Deposit date:
-
2019-03-14
Terms of use
- Copyright holder:
- Tuemer et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record