- Abstract:
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Background Artemisinin resistance in falciparum malaria is associated with kelch13 propeller mutations, reduced ring stage parasite killing, and, consequently, slow parasite clearance. We assessed how parasite age affects parasite clearance in artemisinin resistance. Methods Developmental stages of Plasmodium falciparum parasites on blood films performed at hospital admission and their kelch13 genotypes were assessed for 816 patients enrolled in a multinatio... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 226.3KB)
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- Publisher copy:
- 10.1093/infdis/jiy673
-
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- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Journal of Infectious Diseases Journal website
- Volume:
- 219
- Issue:
- 9
- Pages:
- 1483–1489
- Publication date:
- 2019-01-17
- Acceptance date:
- 2018-12-22
- DOI:
- EISSN:
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1537-6613
- ISSN:
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0022-1899
- Pubs id:
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pubs:965432
- URN:
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uri:60320fea-c980-423d-8ae9-5c327f9ae0e6
- UUID:
-
uuid:60320fea-c980-423d-8ae9-5c327f9ae0e6
- Local pid:
- pubs:965432
- Language:
- English
- Keywords:
- Copyright holder:
- Intharabut et al.
- Copyright date:
- 2019
- Notes:
- Copyright © 2019 The Authors. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Artemisinin resistance and stage dependency of parasite clearance in Falciparum malaria
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Department for International Development
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