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Human genetic susceptibility to tuberculous meningitis in Vietnamese population

Abstract:

A case-control study of TLR2 candidate found that genotype 597CC was associated with susceptibility to tuberculous meningitis (TBM) (OR = 3.26) 1). SNP C558T on TIRAP was found to be associated with increased susceptibility to TBM in this same Vietnamese cohort 2) (OR= 3.02). The co-inheritance of TLR2 SNP T597C and TIRAP SNP C558T increases susceptibility to TBM (OR = 5.4). The interaction between polymorphisms on TLR2 and TIRAP in TB patients and M. tuberculosis strains shows that individua...

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Journal:
Kekkaku
Volume:
85
Issue:
3
Pages:
171-175
Publication date:
2010-01-01
ISSN:
0022-9776
URN:
uuid:600a6a6a-7d92-4b0b-876a-bddb552c48c2
Source identifiers:
340138
Local pid:
pubs:340138
Language:
English

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