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A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii.

Abstract:

BACKGROUND: Apicomplexans contain only a core set of factors involved in vesicular traffic. Yet these obligate intracellular parasites evolved a set of unique secretory organelles (micronemes, rhoptries, and dense granules) that are required for invasion and modulation of the host cell. Apicomplexa replicate by budding from or within a single mother cell, and secretory organelles are synthesized de novo at the final stage of division. To date, the molecular basis for their biogenesis is unkno...

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Publisher copy:
10.1016/j.cub.2009.01.039

Authors


Breinich, MS More by this author
Ferguson, DJ More by this author
van Dooren, GG More by this author
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Journal:
Current biology : CB
Volume:
19
Issue:
4
Pages:
277-286
Publication date:
2009-02-05
DOI:
EISSN:
1879-0445
ISSN:
0960-9822
URN:
uuid:5ffde958-d84c-40f1-b5b5-65b1ee62baac
Source identifiers:
246512
Local pid:
pubs:246512

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