Journal article
CISH and susceptibility to infectious diseases.
- Abstract:
-
BACKGROUND: The interleukin-2-mediated immune response is critical for host defense against infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a suppressor of cytokine signaling, controls interleukin-2 signaling. METHODS: Using a case-control design, we tested for an association between CISH polymorphisms and susceptibility to major infectious diseases (bacteremia, tuberculosis, and severe malaria) in blood samples from 8402 persons in Gambia, Hong Kong, Keny...
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- Publication status:
- Published
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- Publisher copy:
- 10.1056/nejmoa0905606
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Authors
Bibliographic Details
- Journal:
- New England journal of medicine
- Volume:
- 362
- Issue:
- 22
- Pages:
- 2092-2101
- Publication date:
- 2010-06-01
- DOI:
- EISSN:
-
1533-4406
- ISSN:
-
0028-4793
- Source identifiers:
-
58604
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:58604
- UUID:
-
uuid:5fd54807-f2b9-4f8d-82ce-dbcfd7213faf
- Local pid:
- pubs:58604
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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