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The androgen receptor exon 1 trinucleotide repeat does not act as a modifier of the age of presentation in breast cancer.

Abstract:

The CAG repeat in exon 1 of the androgen receptor (AR) genes has been postulated as both a susceptibility allele and phenotypic modifier in BRCA1-associated breast cancers. We have analysed this repeat in a set of 178 breast cancer cases who have been selected only for age of presentation at 65 years or less. No effect of repeat length on age of presentation was found and there was no association between repeat length and family history. In combination with the data from other workers, our fi...

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Publication status:
Published

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Authors


Radbourne, R More by this author
Merritt, S More by this author
Barclay, E More by this author
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Journal:
European journal of cancer (Oxford, England : 1990)
Volume:
36
Issue:
4
Pages:
533-534
Publication date:
2000-03-05
DOI:
EISSN:
1879-0852
ISSN:
0959-8049
URN:
uuid:5fcb4e54-f097-4c2c-a99f-7daef5e598c5
Source identifiers:
72182
Local pid:
pubs:72182

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