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Journal article

Modeling the effect of hyperoxia on the spin–lattice relaxation rate R1 of tissues

Abstract:

Purpose

Inducing hyperoxia in tissues is common practice in several areas of research, including oxygen-enhanced MRI (OE-MRI), which attempts to use the resulting signal changes to detect regions of tumor hypoxia or pulmonary disease. The linear relationship between PO2 and R1 has been reproduced in phantom solutions and body fluids such as vitreous fluid; however, in tissue and blood experiments, factors such as changes in deoxyhemoglobin levels can also affect the ΔR... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/mrm.29315

Authors


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Role:
Author
ORCID:
0000-0001-5970-9100
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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Oxford college:
St Catherine's College
Role:
Author
ORCID:
0000-0003-3371-5929
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Name:
Medical Research Council Canada
Publisher:
Wiley
Journal:
Magnetic Resonance in Medicine More from this journal
Volume:
88
Issue:
4
Pages:
1867-1885
Publication date:
2022-06-09
Acceptance date:
2022-05-09
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
Pmid:
35678239
Language:
English
Keywords:
Pubs id:
1264936
Local pid:
pubs:1264936
Deposit date:
2022-11-04

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