Journal article icon

Journal article

Elevated gamma band power in humans receiving naloxone suggests dorsal periaqueductal and periventricular gray deep brain stimulation produced analgesia is opioid mediated.

Abstract:

BACKGROUND: The midbrain periaqueductal and periventricular gray (PAVG) region is important for pain and autonomic modulation. We have previously described changes in blood pressure dependent upon dorsal or ventral electrode positioning with PAVG deep brain stimulation (DBS), yet controversy exists about whether DBS acts via endogenous opioid release. METHOD AND RESULTS: We combined local field potential (LFP) recording from PAVG DBS electrodes in humans with naloxone and saline infusions to...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Pereira, EA More by this author
Peachey, T More by this author
Shlugman, D More by this author
Expand authors...
Journal:
Experimental neurology
Volume:
239
Issue:
1
Pages:
248-255
Publication date:
2013-01-05
DOI:
EISSN:
1090-2430
ISSN:
0014-4886
URN:
uuid:5fac0944-0dba-4096-be23-23ae0a987680
Source identifiers:
358452
Local pid:
pubs:358452

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP