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Phospholipid complexation and association with apolipoprotein C-II: insights from mass spectrometry.

Abstract:

The interactions between phospholipid molecules in suspensions have been studied by using mass spectrometry. Electrospray mass spectra of homogeneous preparations formed from three different phospholipid molecules demonstrate that under certain conditions interactions between 90 and 100 lipid molecules can be preserved. In the presence of apolipoprotein C-II, a phospholipid binding protein, a series of lipid molecules and the protein were observed in complexes. The specificity of binding was ...

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Publication status:
Published

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Authors


Hanson, CL More by this author
Hatters, DM More by this author
Howlett, GJ More by this author
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Journal:
Biophysical journal
Volume:
85
Issue:
6
Pages:
3802-3812
Publication date:
2003-12-05
DOI:
EISSN:
1542-0086
ISSN:
0006-3495
URN:
uuid:5faa9032-2995-4d73-adc5-9332dc2df114
Source identifiers:
59253
Local pid:
pubs:59253

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