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Intrathoracic pressure swings induced by simulated obstructive sleep apnoea promote arrhythmias in paroxysmal atrial fibrillation

Abstract:

AIMS: There is preliminary evidence for a link between obstructive sleep apnoea (OSA) and arrhythmias such as paroxysmal atrial fibrillation (PAF) and sudden cardiac death but underlying mechanisms remain largely unknown. METHODS AND RESULTS: In this interventional crossover study, we evaluated whether intrathoracic pressure changes, induced by simulated OSA, trigger premature cardiac beats, and alter measures of ventricular repolarization [QTc and Tpeak-to-Tend (TpTec) intervals] in patients...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/europace/euv122

Authors


Publisher:
Oxford University Press
Journal:
Europace More from this journal
Volume:
18
Issue:
1
Pages:
64–70
Publication date:
2015-05-19
DOI:
EISSN:
1532-2092
ISSN:
1099-5129
Language:
English
Keywords:
Pubs id:
pubs:526213
UUID:
uuid:5fa1e7f5-9ce0-4b6b-ba19-5a8f88449ddd
Local pid:
pubs:526213
Source identifiers:
526213
Deposit date:
2015-11-24

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