Journal article
Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs
- Abstract:
- Here we identify hundreds of RNA G-quadruplex (rG4) candidates in microRNAs (miRNAs), characterize the miRNA structure and miRNA–mRNA interactions on several mammalian-conserved miRNAs, and reveal the formation of rG4s in miRNAs. Notably, we study the effect of these rG4s in cells and uncover the role of rG4s in miRNA-mediated post-transcriptional regulation.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 1.0MB, Terms of use)
-
- Publisher copy:
- 10.1039/c8cc04635b
Authors
Bibliographic Details
- Publisher:
- Royal Society of Chemistry
- Journal:
- Chemical Communications More from this journal
- Volume:
- 54
- Issue:
- 77
- Pages:
- 10878-10881
- Publication date:
- 2018-08-27
- Acceptance date:
- 2018-08-25
- DOI:
- EISSN:
-
1364-548X
- ISSN:
-
1359-7345
- Pmid:
-
30204160
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:919656
- UUID:
-
uuid:5f98cab1-d8e9-43fe-8457-4debc17d586e
- Local pid:
-
pubs:919656
- Source identifiers:
-
919656
- Deposit date:
-
2019-03-14
Terms of use
- Copyright holder:
- Chan et al
- Copyright date:
- 2018
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from the Royal Society of Chemistry at: https://doi.org/10.1039/c8cc04635b
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record