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Journal article

Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function.

Abstract:

At present, approximately 150 different members of the adhesion-G protein-coupled receptor (GPCR) family have been identified in metazoans. Surprisingly, very little is known about their function, although they all possess large extracellular domains coupled to a seven-transmembrane domain, suggesting a potential role in cell adhesion and signaling. Here, we demonstrate how the human-restricted adhesion-GPCR, EMR2 (epidermal growth factor-like module-containing mucin-like hormone receptor), r...

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Publication status:
Published

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Publisher copy:
10.1096/fj.07-9435com

Authors


Davies, JQ More by this author
Hayhoe, RP More by this author
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Journal:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Volume:
22
Issue:
3
Pages:
741-751
Publication date:
2008-03-05
DOI:
EISSN:
1530-6860
ISSN:
0892-6638
URN:
uuid:5f4b1789-e007-43a0-84ee-3a3a9f15f719
Source identifiers:
5422
Local pid:
pubs:5422

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