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Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials.

Abstract:

BACKGROUND: After breast-conserving surgery, radiotherapy reduces recurrence and breast cancer death, but it may do so more for some groups of women than for others. We describe the absolute magnitude of these reductions according to various prognostic and other patient characteristics, and relate the absolute reduction in 15-year risk of breast cancer death to the absolute reduction in 10-year recurrence risk. METHODS: We undertook a meta-analysis of individual patient data for 10,801 women ...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Arriagada, R More by this author
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Journal:
Lancet
Volume:
378
Issue:
9804
Pages:
1707-1716
Publication date:
2011-11-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:5f309702-675b-430b-8d2a-2a35a50a9dca
Source identifiers:
272374
Local pid:
pubs:272374

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