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Host-parasite interaction and morbidity in malaria endemic areas.

Abstract:

Severe morbidity due to Plasmodium falciparum is a major health problem in African children. The patterns of morbidity in endemic areas are modified by the immune response, and vary markedly with transmission intensity. Severe disease falls into three overlapping syndromes: coma, respiratory distress, and severe anaemia. Recently, it has become clear that metabolic acidosis plays a major role in the pathogenesis of severe disease and is particularly important in the overlap between the differ...

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Publication status:
Published

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Publisher copy:
10.1098/rstb.1997.0124

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Volume:
352
Issue:
1359
Pages:
1385-1394
Publication date:
1997-09-05
DOI:
EISSN:
1471-2970
ISSN:
0962-8436
URN:
uuid:5f278510-7190-456b-8578-b7f7394f616b
Source identifiers:
45780
Local pid:
pubs:45780

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