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Crossed unilateral lesions of medial forebrain bundle and either inferior temporal or frontal cortex impair object recognition memory in Rhesus monkeys.

Abstract:

In monkeys, section of the fornix, amygdala and anterior temporal stem results in a severe anterograde amnesia. Immunolesions of the cholinergic cells of the basal forebrain suggest that this amnesia is a result of isolating the inferior temporal cortex and medial temporal lobe from their cholinergic basal forebrain afferents. In this experiment, six monkeys were trained in a delayed match-to-sample task and then received a section of the medial forebrain bundle in one hemisphere and an ablat...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Behavioural brain research
Volume:
121
Issue:
1-2
Pages:
1-10
Publication date:
2001-06-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:5efd79d4-5df2-4c6b-97d1-1750cbd5d08b
Source identifiers:
2888
Local pid:
pubs:2888

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