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The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans

Abstract:

Aims To investigate the effect of kisspeptin on glucose‐stimulated insulin secretion and appetite in humans.

Materials and methods In 15 healthy men (age: 25.2 ± 1.1 years; BMI: 22.3 ± 0.5 kg m−2), we compared the effects of 1 nmol kg−1 h−1 kisspeptin versus vehicle administration on glucose‐stimulated insulin secretion, metabolites, gut hormones, appetite and food intake. In addition, we assessed the effect of kisspeptin on glucose‐stimulated insul...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1111/dom.13460

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Role:
Author
ORCID:
0000-0001-7599-0166
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Grant:
03/DHCS/03/G121/48
RP‐2014‐05‐001
ACF-2015-21-004
CL-2015-21-003
ACF-2014-21-004
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Grant:
MR/J0003042/1
MR/K001981/1
MR/L020149/1
MR/M004171/1
MR/N00275X/1
MR/N020472/1
MR/R000484/1
Publisher:
Wiley Publisher's website
Journal:
Diabetes, Obesity and Metabolism Journal website
Volume:
20
Issue:
12
Pages:
2800-2810
Publication date:
2018-11-11
Acceptance date:
2018-07-04
DOI:
EISSN:
1463-1326
ISSN:
1462-8902
Pubs id:
pubs:864962
URN:
uri:5ee668df-78cc-44ac-b003-63b8bfabeb9d
UUID:
uuid:5ee668df-78cc-44ac-b003-63b8bfabeb9d
Local pid:
pubs:864962

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