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Topographical variation in glycosaminoglycan content in human articular cartilage.

Abstract:

The weight-bearing status of articular cartilage has been shown to affect its biochemical composition. We have investigated the topographical variation of sulphated glycosaminoglycan (GAG) relative to the DNA content of the chondrocyte in human distal femoral articular cartilage. Paired specimens of distal femoral articular cartilage, from weight-bearing and non-weight-bearing regions, were obtained from 13 patients undergoing above-knee amputation. After papain enzyme digestion, spectrophoto...

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Publication status:
Published

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Authors


Rogers, BA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Cannon, SR More by this author
Briggs, TW More by this author
Journal:
The Journal of bone and joint surgery. British volume
Volume:
88
Issue:
12
Pages:
1670-1674
Publication date:
2006-12-05
DOI:
ISSN:
0301-620X
URN:
uuid:5edf69d3-d59d-4463-af7f-be7191408a00
Source identifiers:
227014
Local pid:
pubs:227014

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