Journal article icon

Journal article

Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration.

Abstract:

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. In its severest form, choroidal neovessels breach the macular Bruch's membrane, an extracellular matrix compartment comprised of elastin and collagen laminae, and grow into the retina. We sought to determine whether structural properties of the elastic lamina (EL) correspond to the region of the macula that is predilected toward degeneration in AMD. Morphometric assessment of the macular and extramacular re...

Expand abstract

Actions


Access Document


Authors


Expand authors...
Journal:
The American journal of pathology
Volume:
166
Issue:
1
Pages:
241-251
Publication date:
2005-01-05
DOI:
EISSN:
1525-2191
ISSN:
0002-9440
URN:
uuid:5eb9abd9-da02-4bef-a2d3-c8b0adf57b0d
Source identifiers:
254213
Local pid:
pubs:254213

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP