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Journal article

Insulin secretion: Function and therapy of pancreatic beta-cells in diabetes

Abstract:

Insulin is secreted from the beta-cells of the pancreatic islets in response to an elevation of blood glucose concentration. This review describes a current view of the metabolic control of insulin secretion and the molecular mechanisms involved, including the role played by the beta-cell to ensure correct release of insulin as a result of electrical signals. It then considers what goes wrong in type 2 diabetes, a disease resulting from insufficient insulin secretion. It focuses on the influe...

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Journal:
British Journal of Diabetes and Vascular Disease
Volume:
5
Issue:
4
Pages:
187-191
Publication date:
2005-07-01
ISSN:
1474-6514
Source identifiers:
93091
Language:
English
Keywords:
Pubs id:
pubs:93091
UUID:
uuid:5e969457-2ccc-44f2-9f47-782a55115d53
Local pid:
pubs:93091
Deposit date:
2012-12-19

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