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Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.

Abstract:

BACKGROUND: Artemisinin-based combinations are judged the best treatments for multidrug-resistant Plasmodium falciparum malaria. Artesunate-mefloquine is widely recommended in southeast Asia, but its high cost and tolerability profile remain obstacles to widespread deployment. To assess whether dihydroartemisinin-piperaquine is a suitable alternative to artesunate-mefloquine, we compared the safety, tolerability, efficacy, and effectiveness of the two regimens for the treatment of uncomplica...

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Publication status:
Published

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Journal:
Lancet
Volume:
367
Issue:
9528
Pages:
2075-2085
Publication date:
2006-06-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:5e678bea-dcd3-400e-baa9-e5df2ec81311
Source identifiers:
26075
Local pid:
pubs:26075

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