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Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years.

Abstract:

Alemtuzumab is a powerful lymphocyte depleting antibody currently being evaluated in solid organ transplantation. This paper describes 5-year results of a single center study of alemtuzumab as induction in renal transplantation. Thirty-three renal transplant recipients received 20 mg alemtuzumab on day 0 and 1, followed by half-dose cyclosporin monotherapy (trough concentration 75-125 ng/mL) from day 3. They were compared in a retrospective contemporaneous-controlled manner with 66 kidney tra...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Volume:
5
Issue:
6
Pages:
1347-1353
Publication date:
2005-06-05
DOI:
EISSN:
1600-6143
ISSN:
1600-6135
URN:
uuid:5e291ad5-f0b5-48eb-a6f0-f90b5d785204
Source identifiers:
6077
Local pid:
pubs:6077

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