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cell cycle model for somitogenesis: Mathematical formulation and numerical simulation

Abstract:
After many years of research, the mechanisms that generate a periodic pattern of repeated elements (somites) along the length of the embryonic body axis is still one of the major unresolved problems in developmental biology. Here we present a mathematical formulation of the cell cycle model for somitogenesis proposed in Development 105 (1989), 119-130. Somite precursor cells in the node are asynchronous, and therefore,

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Journal:
Journal of theoretical biology
Volume:
207
Issue:
3
Pages:
305-316
Publication date:
2000-01-01
URN:
uuid:5e26df71-cf05-4b72-99e0-8ecd84c82848
Local pid:
cs:4279

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