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Animal models of maternal nutrition and altered offspring bone structure--bone development across the lifecourse.

Abstract:
It is widely accepted that the likelihood of offspring developing heart disease, stroke, or diabetes in later life, is influenced by the their in utero environment and maternal nutrition. There is increasing epidemiological evidence that osteoporosis in the offspring may also be influenced by the mother's nutrition during pregnancy. This review provides evidence from a range of animal models that supports the epidemiological data; suggesting that lifelong bone development and growth in offspring is determined during gestation.

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
European cells and materials
Volume:
22
Pages:
321-332
Publication date:
2011-01-01
EISSN:
1473-2262
URN:
uuid:5dc8fe55-0e81-44d7-bad0-7a383fd6de9f
Source identifiers:
216054
Local pid:
pubs:216054

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