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A novel common variant in DCST2 is associated with length in early life and height in adulthood.

Abstract:

Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 × 10(-6)) for birth length, of which three were novel and four were in or near loci known to be associated with adult height ...

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Publisher copy:
10.1093/hmg/ddu510

Authors


van der Valk, RJ More by this author
Kreiner-Møller, E More by this author
Kooijman, MN More by this author
Stergiakouli, E More by this author
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Journal:
Human molecular genetics
Publication date:
2014-10-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:5dba6ef0-5375-4614-a7bd-d9865fbbf44f
Source identifiers:
485923
Local pid:
pubs:485923

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