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Long-term synaptic plasticity in hippocampal interneurons.

Abstract:

Rapid memory formation relies, at least in part, on long-term potentiation (LTP) of excitatory synapses. Inhibitory interneurons of the hippocampus, which are essential for information processing, have recently been found to exhibit not one, but two forms of LTP. One form resembles LTP that occurs in pyramidal neurons, which depends on N-methyl-D-aspartate receptors and is triggered by coincident pre- and postsynaptic activity. The other depends on Ca2+ influx through glutamate receptors that...

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Publication status:
Published

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Publisher copy:
10.1038/nrn2207

Authors


Kullmann, DM More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Journal:
Nature reviews. Neuroscience
Volume:
8
Issue:
9
Pages:
687-699
Publication date:
2007-09-05
DOI:
EISSN:
1471-0048
ISSN:
1471-003X
URN:
uuid:5daa64e7-bf05-4bbd-8250-c9d3dacf9089
Source identifiers:
185294
Local pid:
pubs:185294

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