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School-aged children: a reservoir for continued circulation of Haemophilus influenzae type b in the United Kingdom.

Abstract:

BACKGROUND: A resurgence of Haemophilus influenzae type b (Hib) disease occurred in the United Kingdom between 1999 and 2003 and was partially attributed to lower immunogenicity of combination vaccines. The reservoir for Hib that led to transmission in this period is unknown. METHODS: We estimated the point prevalence of Hib carriage in school-aged children and adults, using oropharyngeal swabbing and selective media. We characterized the Hib isolates by multilocus sequence typing (MLST) and ...

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Publication status:
Published

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Publisher copy:
10.1086/586716

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Journal:
The Journal of infectious diseases
Volume:
197
Issue:
9
Pages:
1275-1281
Publication date:
2008-05-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:5d9efbab-eb31-4033-a8f5-2ef93c24e1e6
Source identifiers:
66482
Local pid:
pubs:66482

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