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Short-term exposure to exogenous lipids in premature infants and long-term changes in aortic and cardiac function.

Abstract:

OBJECTIVE: Intravenous lipid use is associated with an acute hyperlipidemia, but long-term consequences have not been studied. We investigated whether elevated lipids in humans during the critical period of preterm neonatal life have a long-term impact on aortic and myocardial function relevant to adult disease. METHODS AND RESULTS: We followed up 102 subjects born prematurely and now aged 23 to 28 years. Eighteen received intravenous lipids as neonates and were matched to controls with equiv...

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Publication status:
Published

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Publisher copy:
10.1161/atvbaha.111.227298

Authors


Lewandowski, AJ More by this author
Kylintireas, I More by this author
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Journal:
Arteriosclerosis, thrombosis, and vascular biology
Volume:
31
Issue:
9
Pages:
2125-2135
Publication date:
2011-09-05
DOI:
EISSN:
1524-4636
ISSN:
1079-5642
URN:
uuid:5d862f31-96f0-4417-a80e-a8e5d86b28a4
Source identifiers:
170165
Local pid:
pubs:170165

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