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Replication termination and chromosome dimer resolution in the archaeon Sulfolobus solfataricus.

Abstract:

Archaea of the genus Sulfolobus have a single-circular chromosome with three replication origins. All three origins fire in every cell in every cell cycle. Thus, three pairs of replication forks converge and terminate in each replication cycle. Here, we report 2D gel analyses of the replication fork fusion zones located between origins. These indicate that replication termination involves stochastic fork collision. In bacteria, replication termination is linked to chromosome dimer resolution,...

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Publication status:
Published

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Publisher copy:
10.1038/emboj.2010.301

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
The EMBO journal
Volume:
30
Issue:
1
Pages:
145-153
Publication date:
2011-01-05
DOI:
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:5d60e10f-e103-4b86-a859-2c6793102a91
Source identifiers:
103607
Local pid:
pubs:103607

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