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Journal article

A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis.

Abstract:

OBJECTIVE: We tested whether it is possible to differentiate relapsing-remitting (RR) from secondary progressive (SP) disease stages in patients with multiple sclerosis (MS) using a combination of nuclear magnetic resonance (NMR) metabolomics and partial least squares discriminant analysis (PLS-DA) of biofluids, which makes no assumptions on the underlying mechanisms of disease. METHODS: Serum samples were obtained from patients with primary progressive MS (PPMS), SPMS, and RRMS; patients wit...

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Publication status:
Published

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Journal:
Neurology
Volume:
83
Issue:
17
Pages:
1492-1499
Publication date:
2014-10-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:5d53b634-abb9-4a8c-8512-ffff819bc178
Source identifiers:
485211
Local pid:
pubs:485211
Language:
English

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