- Abstract:
-
OBJECTIVE: We tested whether it is possible to differentiate relapsing-remitting (RR) from secondary progressive (SP) disease stages in patients with multiple sclerosis (MS) using a combination of nuclear magnetic resonance (NMR) metabolomics and partial least squares discriminant analysis (PLS-DA) of biofluids, which makes no assumptions on the underlying mechanisms of disease. METHODS: Serum samples were obtained from patients with primary progressive MS (PPMS), SPMS, and RRMS; patients wit...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1212/wnl.0000000000000905
-
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- Journal:
- Neurology
- Volume:
- 83
- Issue:
- 17
- Pages:
- 1492-1499
- Publication date:
- 2014-10-05
- DOI:
- EISSN:
-
1526-632X
- ISSN:
-
0028-3878
- URN:
-
uuid:5d53b634-abb9-4a8c-8512-ffff819bc178
- Source identifiers:
-
485211
- Local pid:
- pubs:485211
- Language:
- English
- Copyright date:
- 2014
Journal article
A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis.
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