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Journal article

Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk.

Abstract:

It has recently been suggested that the low-frequency c.136-14_136-13insC variant in high-mobility group A1 (HMGA1) may strongly contribute to insulin resistance and type 2 diabetes risk. In our study, we attempted to confirm that HMGA1 is a novel type 2 diabetes locus in French Caucasians. The gene was sequenced in 368 type 2 diabetic case subjects with a family history of type 2 diabetes and 372 normoglycemic control subjects without a family history of type 2 diabetes. None of the 41 genet...

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Publication status:
Published

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Publisher copy:
10.2337/db11-0728

Authors


Marquez, M More by this author
Huyvaert, M More by this author
Pearson, RD More by this author
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Journal:
Diabetes
Volume:
61
Issue:
2
Pages:
524-530
Publication date:
2012-02-05
DOI:
EISSN:
1939-327X
ISSN:
0012-1797
URN:
uuid:5d518b0d-2657-4b13-95b0-65b15b868a77
Source identifiers:
254564
Local pid:
pubs:254564

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