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Chemokine receptor polymorphisms and human immunodeficiency virus disease progression.

Abstract:

The role of polymorphisms in genes encoding chemokines and their receptors (CCR2B, SDF-1, and the promoter region of CCR5) in human immunodeficiency virus (HIV) disease progression was studied in 132 white HIV type 1 (HIV-1)-infected participants from a United Kingdom cohort study. Genotyping was done by use of amplification refractory mutation system-polymerase chain reaction with sequence-specific primers, and Cox proportional hazards models were used to examine the impact of polymorphisms ...

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Publication status:
Published

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Publisher copy:
10.1086/314997

Authors


Easterbrook, PJ More by this author
Rostron, T More by this author
Gazzard, BG More by this author
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Volume:
180
Issue:
4
Pages:
1096-1105
Publication date:
1999-10-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:5d0137c6-b3b1-458d-a1fb-8e418fe330e5
Source identifiers:
15723
Local pid:
pubs:15723

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