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Glucopyranose spirohydantoins: Specific inhibitors of glycogen phosphorylase

Abstract:
A short synthesis of the spirohydantoin of glucopyranose 1β [a potent and specific inhibitor of glycogen phosphorylase], together with its inactive anomer 1α, from a readily available heptonolactone is described; this is the first synthesis of a spirohydantoin of a pyranose in which the pyranose ring is formed after the hydantoin ring.
Publication status:
Published

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Publisher copy:
10.1055/s-1997-940277

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Journal:
SYNLETT
Volume:
1997
Issue:
5
Pages:
485-and
Publication date:
1997-05-05
DOI:
EISSN:
1437-2096
ISSN:
0936-5214
URN:
uuid:5ce7834c-b123-47f3-8997-06d23b11ca21
Source identifiers:
45621
Local pid:
pubs:45621

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