Journal article icon

Journal article

Fate-restricted neural progenitors in the mammalian cerebral cortex.

Abstract:

During development of the mammalian cerebral cortex, radial glial cells (RGCs) generate layer-specific subtypes of excitatory neurons in a defined temporal sequence, in which lower-layer neurons are formed before upper-layer neurons. It has been proposed that neuronal subtype fate is determined by birthdate through progressive restriction of the neurogenic potential of a common RGC progenitor. Here, we demonstrate that the murine cerebral cortex contains RGC sublineages with distinct fate pot...

Expand abstract

Actions


Access Document


Publisher copy:
10.1126/science.1223616

Authors


Franco, SJ More by this author
Gil-Sanz, C More by this author
Martinez-Garay, I More by this author
Espinosa, A More by this author
Harkins-Perry, SR More by this author
Expand authors...
Journal:
Science (New York, N.Y.)
Volume:
337
Issue:
6095
Pages:
746-749
Publication date:
2012-08-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:5cce39fc-1e69-4e2a-b62d-30721536e9a0
Source identifiers:
426685
Local pid:
pubs:426685

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP