Journal article icon

Journal article

Epstein-Barr virus can establish infection in the absence of a classical memory B-cell population.

Abstract:

Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that persists in the body for life after primary infection. The primary site of EBV persistence is the memory B lymphocyte, but whether the virus initially infects naïve or memory B cells is still disputed. We have analyzed EBV infection in nine cases of X-linked hyper-immunoglobulin M (hyper-IgM) syndrome who, due to a mutation in CD40 ligand gene, do not have a classical, class-switched memory B-cell population (IgD(-) CD27(+)). We ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Expand authors...
Journal:
Journal of virology
Volume:
79
Issue:
17
Pages:
11128-11134
Publication date:
2005-09-01
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Source identifiers:
66649

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP