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The gene for theta-globin is transcribed in human fetal erythroid tissues.

Abstract:

A new gene like the alpha-globin gene has been identified in higher primates at the 3' end of the alpha-globin gene cluster. There is some controversy as to whether this gene, theta, is a functional globin gene or a non-functional pseudogene. The high degree of sequence conservation displayed by theta between primates and various mammals, such as horse and rabbit, suggests that this gene is functional in some species. Furthermore, theta encodes a 141-amino-acid polypeptide in sequence similar...

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Publication status:
Published

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Publisher copy:
10.1038/329551a0

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Whitelaw, E More by this author
Journal:
Nature
Volume:
329
Issue:
6139
Pages:
551-554
Publication date:
1987
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:5cb0a4e1-7c23-4b0c-9c36-fd9a9e370ea0
Source identifiers:
25526
Local pid:
pubs:25526

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