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Niacin in cardiovascular disease: Recent preclinical and clinical developments

Abstract:

Niacin has been used for more than 50 years in the treatment of cardiovascular disease, although its use has largely been superseded by better-tolerated lipid-modulating interventions. There has been a renewed interest in the HDL-cholesterol raising properties of niacin, with the appreciation that substantial cardiovascular risk remains despite effective treatment of LDL-cholesterol. This coincides with increasing evidence that the complex functional properties of HDL are not well reflected b...

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Publisher copy:
10.1161/ATVBAHA.111.236315

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Journal:
Arteriosclerosis, Thrombosis, and Vascular Biology
Volume:
32
Issue:
3
Pages:
582-588
Publication date:
2012-03-05
DOI:
EISSN:
1524-4636
ISSN:
1079-5642
URN:
uuid:5c77b75b-1575-4cda-a9d0-c72e76eb0564
Source identifiers:
320809
Local pid:
pubs:320809

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