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A common brain network links development, aging, and vulnerability to disease.

Abstract:

Several theories link processes of development and aging in humans. In neuroscience, one model posits for instance that healthy age-related brain degeneration mirrors development, with the areas of the brain thought to develop later also degenerating earlier. However, intrinsic evidence for such a link between healthy aging and development in brain structure remains elusive. Here, we show that a data-driven analysis of brain structural variation across 484 healthy participants (8-85 y) reveal...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.1410378111

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Groves, AR More by this author
Tamnes, CK More by this author
Westlye, LT More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
111
Issue:
49
Pages:
17648-17653
Publication date:
2014-12-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:5c4e5115-8b56-4683-b4be-3d75740bb782
Source identifiers:
491741
Local pid:
pubs:491741

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