Journal article icon

Journal article

Glycolipid receptor depletion as an approach to specific antimicrobial therapy.

Abstract:

Mucosal pathogens recognize glycoconjugate receptors at the site of infection, and attachment is an essential first step in disease pathogenesis. Inhibition of attachment may prevent disease, and several approaches have been explored. This review discusses the prevention of bacterial attachment and disease by agents that modify the glycosylation of cell surface glycoconjugates. Glycosylation inhibitors were tested in the urinary tract infection model, where P-fimbriated Escherichia coli rely ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
FEMS microbiology letters
Volume:
258
Issue:
1
Pages:
1-8
Publication date:
2006-05-01
DOI:
EISSN:
1574-6968
ISSN:
0378-1097
Source identifiers:
185138
Language:
English
Keywords:
Pubs id:
pubs:185138
UUID:
uuid:5c34c538-6519-485e-ade6-dea5f7eb3314
Local pid:
pubs:185138
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP