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Journal article

Immunodrugs: therapeutic VLP-based vaccines for chronic diseases.

Abstract:

Worldwide, the prevalence of noncommunicable chronic diseases is increasing. The use of vaccines to induce autoantibodies that neutralize disease-related proteins offers a means to effectively and affordably treat such diseases. Twenty vaccines designed to induce therapeutic autoantibodies were clinically tested in the past 12 years. Immunodrugs are therapeutic vaccines comprising virus-like particles (VLPs) covalently conjugated with self-antigens that induce neutralizing autoantibody respon...

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Publication status:
Published

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Authors


Jennings, GT More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Journal:
Annual review of pharmacology and toxicology
Volume:
49
Issue:
1
Pages:
303-326
Publication date:
2009
DOI:
EISSN:
1545-4304
ISSN:
0362-1642
URN:
uuid:5c22f0f4-4eb0-48a9-8fd1-4312f981d473
Source identifiers:
422397
Local pid:
pubs:422397

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