Journal article
Murine IL-10 gene transfer inhibits established collagen-induced arthritis and reduces adenovirus-mediated inflammatory responses in mouse liver.
- Abstract:
-
The effects of homologous IL-10 administration during an established autoimmune disease are controversial, given its reported immunostimulatory and immunosuppressive properties. Studies of collagen-induced arthritis have shown efficacy with repeated administrations of IL-10; however, when the EBV IL-10 homologue was administered via adenovirus gene transfer technology the results were equivocal. Therefore, the present study was undertaken to elucidate the effects of prolonged homologous IL-10...
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- Publication status:
- Published
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- Publisher copy:
- 10.4049/jimmunol.166.10.5970
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Authors
Bibliographic Details
- Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 166
- Issue:
- 10
- Pages:
- 5970-5978
- Publication date:
- 2001-05-05
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:5c19adf0-f411-4f03-a0c7-cc3cdac01638
- Source identifiers:
-
224144
- Local pid:
- pubs:224144
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2001
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