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Journal article

QTL analysis identifies multiple behavioral dimensions in ethological tests of anxiety in laboratory mice.

Abstract:

BACKGROUND: Ethological tests of anxiety-related behaviors, such as the open field arena and elevated plus maze, are often carried out on transgenic animals in the attempt to correlate gene function with a behavioral phenotype. However, the interpretation of such tests is problematic, as it is probable that different tests measure different aspects of behavior; indeed, anxiety may not be a unitary phenomenon. Here, we address these questions by asking whether behaviors in five ethological te...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Journal:
Current biology : CB
Volume:
11
Issue:
10
Pages:
725-734
Publication date:
2001-05-05
DOI:
EISSN:
1879-0445
ISSN:
0960-9822
URN:
uuid:5bf66202-fd9e-4eb4-8398-a395dc65fee4
Source identifiers:
31891
Local pid:
pubs:31891

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