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Journal article

Protein targeting of an unusual, evolutionarily conserved adenylate kinase to a eukaryotic flagellum.

Abstract:

The eukaryotic flagellum is a large structure into which specific constituent proteins must be targeted, transported and assembled after their synthesis in the cytoplasm. Using Trypanosoma brucei and a proteomic approach, we have identified and characterized a novel set of adenylate kinase proteins that are localized to the flagellum. These proteins represent unique isoforms that are targeted to the flagellum by an N-terminal extension to the protein and are incorporated into an extraaxonemal...

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Publication status:
Published

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Publisher copy:
10.1091/mbc.e04-03-0217

Authors


Pullen, TJ More by this author
Ginger, ML More by this author
Gaskell, SJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Molecular biology of the cell
Volume:
15
Issue:
7
Pages:
3257-3265
Publication date:
2004-07-05
DOI:
EISSN:
1939-4586
ISSN:
1059-1524
URN:
uuid:5bd622e9-cbd4-4a97-a961-6b00d0e42608
Source identifiers:
29398
Local pid:
pubs:29398

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