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An exploratory algorithm to identify intra-host recombinant viral sequences.

Abstract:

Since recombination leads to the generation of mosaic genomes that violate the assumption of traditional phylogenetic methods that sequence evolution can be accurately described by a single tree, results and conclusions based on phylogenetic analysis of data sets including recombinant sequences can be severely misleading. Many methods are able to adequately detect recombination between diverse sequences, for example between different HIV-1 subtypes. More problematic is the identification of r...

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Publisher copy:
10.1016/j.ympev.2008.08.017

Authors


Journal:
Molecular phylogenetics and evolution
Volume:
49
Issue:
2
Pages:
618-628
Publication date:
2008-11-05
DOI:
EISSN:
1095-9513
ISSN:
1055-7903
URN:
uuid:5bb5bea2-db02-48ce-b842-eb0f1da03ffc
Source identifiers:
315459
Local pid:
pubs:315459

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