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Phenoxybenzamine is more effective and less harmful than papaverine in the prevention of radial artery vasospasm.

Abstract:

OBJECTIVES: There is an increasing use of arterial conduits for coronary artery bypass grafting, and the radial artery is commonly used as the third graft. The major drawback of the radial artery is its proclivity to spasm. Both papaverine and phenoxybenzamine have been recommended as topical vasodilators in clinical practice. We compared the efficacy of both drugs to prevent radial artery spasm and their ability to preserve endothelial function. METHODS: The ability of both drugs to prevent ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Journal:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Volume:
19
Issue:
4
Pages:
482-486
Publication date:
2001-04-05
DOI:
EISSN:
1873-734X
ISSN:
1010-7940
URN:
uuid:5b977ec0-f941-4624-8579-bc411076e964
Source identifiers:
114253
Local pid:
pubs:114253

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