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Journal article

Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates.

Abstract:

Angiogenesis is an essential component of tumour growth and, consequently, an important target both therapeutically and diagnostically. The cell adhesion molecule α(v)β(3) integrin is a specific marker of angiogenic vessels and the most prevalent vascular integrin that binds the amino acid sequence arginine-glycine-aspartic acid (RGD). Previous studies using RGD-targeted nanoparticles (20-50 nm diameter) of iron oxide (NPIO) for magnetic resonance imaging (MRI) of tumour angiogenesis, have id...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7150/thno.10319

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More from this funder
Funding agency for:
Choudhury, R
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Funding agency for:
Ruparelia, N
Cancer Research UK More from this funder
CR-UK/EPSRC Oxford Cancer Imaging Center More from this funder
Publisher:
Ivyspring International Publisher Publisher's website
Journal:
Theranostics Journal website
Volume:
5
Issue:
5
Pages:
515-529
Publication date:
2015-01-01
DOI:
EISSN:
1838-7640
ISSN:
1838-7640
Source identifiers:
514371
Language:
English
Keywords:
Pubs id:
pubs:514371
UUID:
uuid:5b8bbad5-234a-4cda-afe0-869305f46497
Local pid:
pubs:514371
Deposit date:
2015-11-20

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