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Journal article

Classification and personalized prognosis in myeloproliferative neoplasms

Abstract:

BACKGROUND: Myeloproliferative neoplasms, such as polycythemia vera, essential thrombocythemia, and myelofibrosis, are chronic hematologic cancers with varied progression rates. The genomic characterization of patients with myeloproliferative neoplasms offers the potential for personalized diagnosis, risk stratification, and treatment.

METHODS: We sequenced coding exons from 69 myeloid cancer genes in patients with myeloproliferative neoplasms, comprehensively annotating driver mut...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1056/nejmoa1716614

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
ORCID:
0000-0002-7572-3196
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Publisher:
Massachusetts Medical Society Publisher's website
Journal:
New England Journal of Medicine Journal website
Volume:
379
Issue:
15
Pages:
1416-1430
Publication date:
2018-10-11
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Pmid:
30304655
Source identifiers:
929832
Language:
English
Pubs id:
pubs:929832
UUID:
uuid:5b7095f2-09f3-46eb-bc88-3bbeaa639e63
Local pid:
pubs:929832
Deposit date:
2019-01-09

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