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Phosphorylation and distribution of High-Mobility Group protein HMGN1 in the context of Immediate-Early (IE) gene induction

Abstract:

Eukaryotic genomes are highly organized and packaged into chromatin, a complex structure formed of proteins and DNA, in which the basic repeating unit is the nucleosome. Chromatin can be arranged in condensed or relaxed structures influencing accessibility of proteins that regulate transcription, replication, recombination and repair. One class of transiently chromatin-associated proteins is the High-Mobility Group (HMG) protein family. HMG proteins are subdivided into three subgroups: HMG...

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Institution:
University of Oxford
Research group:
Mahadevan
Oxford college:
Trinity College
Department:
Medical Sciences Division - Biochemistry
Role:
Author

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Role:
Supervisor
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Funding agency for:
Edgar Allan Pogna
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:5b39d964-fd81-4534-bfba-76a32bb60f4e
Local pid:
ora:7243
Language:
English
Keywords:
Subjects:

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