- Abstract:
-
Codon usage bias in Drosophila melanogaster genes has been attributed to negative selection of those codons whose cellular tRNA abundance restricts rates of mRNA translation. Previous studies, which involved limited numbers of genes, can now be compared against analyses of the entire gene complements of 12 Drosophila species whose genome sequences have become available. Using large numbers (6138) of orthologs represented in all 12 species, we establish that the codon preferences of more close...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1534/genetics.107.070466
-
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- Journal:
- Genetics
- Volume:
- 177
- Issue:
- 3
- Pages:
- 1337-1348
- Publication date:
- 2007-11-05
- DOI:
- EISSN:
-
1943-2631
- ISSN:
-
0016-6731
- URN:
-
uuid:5b0fda5b-24ac-4a35-8f4b-f81bea9f5c07
- Source identifiers:
-
237429
- Local pid:
- pubs:237429
- Copyright date:
- 2007
Journal article
Variable strength of translational selection among 12 Drosophila species.
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