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Variable strength of translational selection among 12 Drosophila species.

Abstract:

Codon usage bias in Drosophila melanogaster genes has been attributed to negative selection of those codons whose cellular tRNA abundance restricts rates of mRNA translation. Previous studies, which involved limited numbers of genes, can now be compared against analyses of the entire gene complements of 12 Drosophila species whose genome sequences have become available. Using large numbers (6138) of orthologs represented in all 12 species, we establish that the codon preferences of more close...

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Publication status:
Published

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Publisher copy:
10.1534/genetics.107.070466

Authors


Journal:
Genetics
Volume:
177
Issue:
3
Pages:
1337-1348
Publication date:
2007-11-01
DOI:
EISSN:
1943-2631
ISSN:
0016-6731
Source identifiers:
237429
Language:
English
Keywords:
Pubs id:
pubs:237429
UUID:
uuid:5b0fda5b-24ac-4a35-8f4b-f81bea9f5c07
Local pid:
pubs:237429
Deposit date:
2013-11-16

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